Chemical Modification of Birch Allergen Extract to Reduce Alxoid Allergenicity & Immunogenicity

While some allergoids were related to reduced allergenicity, a clear drop in immunogenicity was observed for all allergoid products compared with the intact allergen vaccine, and the commercial allergoids tested, therefore, don’t fulfill the allergoid concept.Besides this, chemically modified allergen extracts (allergoids) are used when there is some specific type of Alxoid allergy, such as grass or birch allergy.