PK/PD Analysis and Modeling

Pharmacokinetic/pharmacodynamic (PK/PD)-modeling links dose-concentration relationships (PK) and concentration-effect relationships (PD), thereby facilitating the description and prediction of the time course of drug effects resulting from a certain dosing regimen. Pharmacokinetic/pharmacodynamic (PK/PD)-modeling is a part of the drug development process, and is a mathematical technique that predicts changes in drug efficacy over time and dose.